Collagen Types

A considerable amount of the eye is composed of collagen.  Because many eye diseases are related to dysfunction of collagen, it may be useful to categorize these diseases based on the type of collagen and the structures affected.  While this list is not comprehensive, it hopefully is a helpful review.


As you can probably tell, I'm starting to skip around a little bit while I put together these OKAP review articles.  I have a fairly large list of topics to cover, but hopefully these will all be helpful pieces of information.  I decided to skip to aniridia, because it is one of those conditions that seems to be very popular in practice questions.

Corneal Dystrophies Presenting as Recurrent Erosions

Corneal dystrophies are clinically fairly rare (with notable exceptions) but have pretty easily identifiable appearances.  Because we have learned quite a bit about the genetics, inheritance, etc. about many of the dystrophies, this seemed to be a pretty popular topic on tests – though it seemed like in the past few years the number of questions on corneal dystrophies decreased quite a bit.  I don’t know the minds of the test-writers, so who knows if it was a random thing, or if there was more emphasis on clinically significant questions.